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Volume 6 | No. 5 | May 2017


Original Research Article
Heterogeneity of hypothalamic pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencingBrian Y.H. Lam, Irene Cimino, Joseph Polex-Wolf, Sara Nicole Kohnke, Debra Rimmington, Valentine Iyemere, Nicholas Heeley, Chiara Cossetti, Reiner Schulte, Luis R. Saraiva, Darren W. Logan, Clemence Blouet, Stephen O'Rahilly, Anthony P. Coll, Giles S.H. Yeo

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Original Research Article
Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neuronsGillian Cady, Taylor Landeryou, Michael Garratt, John J. Kopchick, Nathan Qi, David Garcia-Galiano, Carol F. Elias, Martin G. Myers Jr., Richard A. Miller, Darleen A. Sandoval, Marianna Sadagurski

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Original Research Article
Plasma 2-arachidonoylglycerol is a biomarker of age and menopause related insulin resistance and dyslipidemia in lean but not in obese men and womenFlaminia Fanelli, Marco Mezzullo, Ilaria Belluomo, Valentina Diana Di Lallo, Margherita Baccini, Daniela Ibarra Gasparini, Elena Casadio, Marianna Mastroroberto, Valentina Vicennati, Alessandra Gambineri, Antonio Maria Morselli-Labate, Renato Pasquali, Uberto Pagotto

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Original Research Article
Acid sphingomyelinase deficiency in Western diet-fed mice protects against adipocyte hypertrophy and diet-induced liver steatosisSvenja Sydor, Jan-Peter Sowa, Dominik A. Megger, Martin Schlattjan, Sami Jafoui, Lena Wingerter, Alexander Carpinteiro, Hideo A. Baba, Lars P. Bechmann, Barbara Sitek, Guido Gerken, Erich Gulbins, Ali Canbay

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Original Research Article
PDK1-FoxO1 pathway in AgRP neurons of arcuate nucleus promotes bone formation via GHRH-GH-IGF1 axisHideyuki Sasanuma, Masanori Nakata, Kumari Parmila, Jun Nakae, Toshihiko Yada

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Brief Communication
Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female miceSigrid Jall, Stephan Sachs, Christoffer Clemmensen, Brian Finan, Frauke Neff, Richard D. DiMarchi, Matthias H. Tschöp, Timo D. Müller, Susanna M. Hofmann

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Brief Communication
Loss of hepatic DEPTOR alters the metabolic transition to fastingAlexandre Caron, Mathilde Mouchiroud, Nicolas Gautier, Sébastien M. Labbé, Romain Villot, Laurie Turcotte, Blandine Secco, Guillaume Lamoureux, Michael Shum, Yves Gélinas, André Marette, Denis Richard, David M. Sabatini, Mathieu Laplante

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