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GLP-1R agonists are known to improve outcomes in ischemic heart disease. The image provided on the cover page summarizes the results of Ussher et al.: the cardiomyocyte GLP-1R is not essential for i) the endogenous physiological response to ischemic or cardiomyopathic injury, ii) GLP-1R-dependent cardioprotection or iii) the pharmacological GLP-1R-dependent increase in HR. In contrast, basal signaling through the atrial cardiomyocyte GLP-1R is essential for control of HR in mice.

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The 60 Second Metabolist
In this section authors briefly report on their work recently published in Molecular Metabolism.

Watch the most recent interview by clicking the video still. The link "referring article" directs you to this author's publication.

Flaminia Fanelli
University of Bologna, Italy
Referring article

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