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This coronal view is a PET/CT fused image of a mouse that has been treated with CL316,243, a specific beta 3 adrenoceptor agonist. The dense areas in the image are accumulations of 11C-MHED, a norepinephrine analogue, in the inguinal subcutaneous white adipose tissue (WAT) depots. In this study, Quarta et al. investigated the potential of PET/CT imaging to capture WAT to brown adipose tissue (BAT) transformation. Their data demonstrate that 11C-MHED PET/CT imaging can be used in vivo to study sympathetic nervous system activity in BAT and the white-to-brown fat transdifferentiation.

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The 60 Second Metabolist
In this section authors briefly report on their work recently published in Molecular Metabolism.

Watch the most recent interview by clicking the video still. The link "referring article" directs you to this author's publication.

Marc Reitman
National Institutes of Health (NIH), Bethesda, USA
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