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This coronal view is a PET/CT fused image of a mouse that has been treated with CL316,243, a specific beta 3 adrenoceptor agonist. The dense areas in the image are accumulations of 11C-MHED, a norepinephrine analogue, in the inguinal subcutaneous white adipose tissue (WAT) depots. In this study, Quarta et al. investigated the potential of PET/CT imaging to capture WAT to brown adipose tissue (BAT) transformation. Their data demonstrate that 11C-MHED PET/CT imaging can be used in vivo to study sympathetic nervous system activity in BAT and the white-to-brown fat transdifferentiation.

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The 60 Second Metabolist
In this section authors briefly report on their work recently published in Molecular Metabolism.

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Marc Reitman
National Institutes of Health (NIH), Bethesda, USA
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