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This image depicts the ObRa knock out (KO) phenotype. ObRa KO mice fed a high-fat diet have significantly increased plasma leptin levels and become slightly more obese than the wild-type mice. These data from Jeffrey Friedman's lab show that the LepRa isoform plays a small but significant role to regulate body weight though the effect of the LepRb isoform knockout is much greater. (Cover art by Charlie Padgett)

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The 60 Second Metabolist
In this section authors briefly report on their work recently published in Molecular Metabolism.

Watch the most recent interview by clicking the video still. The link "referring article" directs you to this author's publication.

Marc Reitman
National Institutes of Health (NIH), Bethesda, USA
Referring article

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