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The cover page shows a confocal image of murine CREB-deficient β-cells with increased apoptosis following cytokine and exendin-4 (GLP-1 analog) treatment (green: insulin-positive beta cells; blue: DAPI-stained nuclei; red: TUNEL-positive nuclei). The experiment demonstrates that the protection conferred by exendin-4 against cytokine-induced cell death is abolished in CREB-deficient islets.

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The 60 Second Metabolist
In this section authors briefly report on their work recently published in Molecular Metabolism.

Watch the most recent interview by clicking the video still. The link "referring article" directs you to this author's publication.

Randy J. Seeley, Henriette Frikke-Schmidt
Department of Surgery, University of Michigan, Ann Arbor, USA
Referring article

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