Article Search


Search

Current Issue

Volume 6 | No. 7 | July 2017


Original Research Article
Grandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal musclePetter S. Alm, Thais de Castro Barbosa, Romain Barrès, Anna Krook, Juleen R. Zierath

Abstract | PDF



Original Research Article
Parental obesity leads to metabolic changes in the F2 generation in DrosophilaRebecca A.S. Palu, Sophia A. Praggastis, Carl S. Thummel

Abstract | PDF



Original Research Article
A high-content small molecule screen identifies novel inducers of definitive endodermAlexander Korostylev, Pallavi U. Mahaddalkar, Oliver Keminer, Kamyar Hadian, Kenji Schorpp, Philip Gribbon, Heiko Lickert

Abstract | PDF



Original Research Article
Mitochondrial transcription factor B2 is essential for mitochondrial and cellular function in pancreatic β-cellsAlexander Korostylev, Pallavi U. Mahaddalkar, Oliver Keminer, Kamyar Hadian, Kenji Schorpp, Philip Gribbon, Heiko Lickert

Abstract | PDF



Original Research Article
AAV-mediated pancreatic overexpression of Igf1 counteracts progression to autoimmune diabetes in miceCristina Mallol, Estefania Casana, Veronica Jimenez, Alba Casellas, Virginia Haurigot, Claudia Jambrina, Victor Sacristan, Meritxell Morró, Judith Agudo, Laia Vilà, Fatima Bosch

Abstract | PDF



Original Research Article
The endogenous preproglucagon system is not essential for gut growth homeostasis in micePernille Wismann, Pernille Barkholt, Thomas Secher, Niels Vrang, Henrik B. Hansen, Palle Bekker Jeppesen, Laurie L. Baggio, Jacqueline A. Koehler, Daniel J. Drucker, Darleen A. Sandoval, Jacob Jelsing

Abstract | PDF



Original Research Article
The human digestive tract has proteases capable of gluten hydrolysisSergio Gutiérrez, Jenifer Pérez-Andrés, Honorina Martínez-Blanco, Miguel Angel Ferrero, Luis Vaquero, Santiago Vivas, Javier Casqueiro, Leandro B. Rodríguez-Aparicio

Abstract | PDF



Original Research Article
Rev-Erb co-regulates muscle regeneration via tethered interaction with the NF-Y cistromeRyan D. Welch, Chun Guo, Monideepa Sengupta, Katherine J. Carpenter, Natalie A. Stephens, Stacy A. Arnett, Marvin J. Meyers, Lauren M. Sparks, Steven R. Smith, Jinsong Zhang, Thomas P. Burris, Colin A. Flaveny

Abstract | PDF



Original Research Article
Loss of ADAMTS5 enhances brown adipose tissue mass and promotes browning of white adipose tissue via CREB signalingDries Bauters, Mathias Cobbaut, Lotte Geys, Johan Van Lint, Bianca Hemmeryckx, H. Roger Lijnen

Abstract | PDF



Original Research Article
ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotypeYulia Haim, Matthias Blüher, Daniel Konrad, Nir Goldstein, Nora Klöting, Ilana Harman-Boehm, Boris Kirshtein, Doron Ginsberg, Tanya Tarnovscki, Yftach Gepner, Iris Shai, Assaf Rudich

Abstract | PDF



Original Research Article
Metformin causes a futile intestinal–hepatic cycle which increases energy expenditure and slows down development of a type 2 diabetes-like statePhilipp Schommers, Anna Thurau, Insa Bultmann-Mellin, Maria Guschlbauer, Andreas R. Klatt, Jan Rozman, Martin Klingenspor, Martin Hrabe de Angelis, Jens Alber, Dirk Gründemann, Anja Sterner-Kock, Rudolf J. Wiesner

Abstract | PDF



Original Research Article
Neonatal GLP1R activation limits adult adiposity by durably altering hypothalamic architectureAndrea V. Rozo, Daniella A. Babu, PoMan A. Suen, David N. Groff, Randy J. Seeley, Rebecca A. Simmons, Patrick Seale, Rexford S. Ahima, Doris A. Stoffers

Abstract | Graphical abstract | PDF



Brief Communication
Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male miceNivedita Seshadri, Michael E. Jonasson, Kristin L. Hunt, Bo Xiang, Steven Cooper, Michael B. Wheeler, Vernon W. Dolinsky, Christine A. Doucette

Abstract | PDF



Brief Communication
Dysregulation of a novel miR-23b/27b-p53 axis impairs muscle stem cell differentiation of humans with type 2 diabetesTora I. Henriksen, Peter K. Davidsen, Maria Pedersen, Heidi S. Schultz, Ninna S. Hansen, Therese J. Larsen, Allan Vaag, Bente K. Pedersen, Søren Nielsen, Camilla Scheele

Abstract | Graphical abstract | PDF



Editorial Board and Credits


PDF



Articles in Press