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Past Issue

Volume 11 | May 2018


Original Research Article
Adipocyte Xbp1s overexpression drives uridine production and reduces obesityYingfeng Deng, Zhao V. Wang, Ruth Gordillo, Yi Zhu, Aktar Ali, Chen Zhang, Xiaoding Wang, Mengle Shao, Zhuzhen Zhang, Puneeth Iyengar, Rana K. Gupta, Jay D. Horton, Joseph A. Hill, Philipp E. Scherer

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Original Research Article
Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesisAntoni Olona, Ximena Terra, Jeong-Hun Ko, Carme Grau-Bové, Montserrat Pinent, Anna Ardevol, Ana Garcia Diaz, Aida Moreno-Moral, Matthew Edin, David Bishop-Bailey, Darryl C. Zeldin, Timothy J. Aitman, Enrico Petretto, Mayte Blay, Jacques Behmoaras

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Original Research Article
Loss of dorsomedial hypothalamic GLP-1 signaling reduces BAT thermogenesis and increases adiposityShin J. Lee, Graciela Sanchez-Watts, Jean-Philippe Krieger, Angelica Pignalosa, Puck N. Norell, Alyssa Cortella, Klaus G. Pettersen, Dubravka Vrdoljak, Matthew R. Hayes, Scott Kanoski, Wolfgang Langhans, Alan G. Watts

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Original Research Article
Insights into the neurochemical signature of the Innervation of Beige FatAneta Stefanidis, Nicole M. Wiedmann, Sonika Tyagi, Andrew M. Allen, Matthew J. Watt, Brian J. Oldfield

Abstract | Graphical abstract | PDF



Original Research Article
Brown adipose tissue derived ANGPTL4 controls glucose and lipid metabolism and regulates thermogenesisAbhishek K. Singh, Binod Aryal, Balkrishna Chaube, Noemi Rotllan, Luis Varela, Tamas L. Horvath, Yajaira Suárez, Carlos Fernández-Hernando

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Original Research Article
Enterochromaffin 5-HT cells – A major target for GLP-1 and gut microbial metabolitesMari L. Lund, Kristoffer L. Egerod, Maja S. Engelstoft, Oksana Dmytriyeva, Elvar Theodorsson, Bhavik A. Patel, Thue W. Schwartz

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Original Research Article
Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreasRune E. Kuhre, Nicolai J. Wewer Albrechtsen, Olav Larsen, Sara L. Jepsen, Emilie Balk-Møller, Daniel B. Andersen, Carolyn F. Deacon, Kristina Schoonjans, Frank Reimann, Fiona M. Gribble, Reidar Albrechtsen, Bolette Hartmann, Mette M. Rosenkilde, Jens J. Holst

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Original Research Article
FGF21, a liver hormone that inhibits alcohol intake in mice, increases in human circulation after acute alcohol ingestion and sustained binge drinking at OktoberfestSusanna Søberg, Emilie S. Andersen, Niels B. Dalgaard, Ida Jarlhelt, Nina L. Hansen, Nina Hoffmann, Tina Vilsbøll, Anne Chenchar, Michal Jensen, Trisha J. Grevengoed, Sam A.J. Trammell, Filip K. Knop, Matthew P. Gillum

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Original Research Article
E2F1 promotes hepatic gluconeogenesis and contributes to hyperglycemia during diabetesAlbert Giralt, Pierre-Damien Denechaud, Isabel C. Lopez-Mejia, Brigitte Delacuisine, Emilie Blanchet, Caroline Bonner, Francois Pattou, Jean-Sébastien Annicotte, Lluis Fajas

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Original Research Article
Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liverArne Hinrichs, Barbara Kessler, Mayuko Kurome, Andreas Blutke, Elisabeth Kemter, Maren Bernau, Armin M. Scholz, Birgit Rathkolb, Simone Renner, Sebastian Bultmann, Heinrich Leonhardt, Martin Hrabĕ de Angelis, Hiroshi Nagashima, Andreas Hoeflich, Werner F. Blum, Martin Bidlingmaier, Rüdiger Wanke, Maik Dahlhoff, Eckhard Wolf

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Original Research Article
VEGF and GLUT1 are highly heritable, inversely correlated and affected by dietary fat intake: Consequences for cognitive function in humansRita Schüler, Nicole Seebeck, Martin A. Osterhoff, Veronica Witte, Agnes Flöel, Andreas Busjahn, Alexander Jais, Jens C. Brüning, Turid Frahnow, Stefan Kabisch, Olga Pivovarova, Silke Hornemann, Michael Kruse, Andreas F.H. Pfeiffer

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Original Research Article
Statin dose reduction with complementary diet therapy: A pilot study of personalized medicineBianca Scolaro, Marina S. Nogueira, Aline Paiva, Adriana Bertolami, Lucia P. Barroso, Tomas Vaisar, Sean P. Heffron, Edward A. Fisher, Inar A. Castro

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Original Research Article
A computational biology approach of a genome-wide screen connected miRNAs to obesity and type 2 diabetesPascal Gottmann, Meriem Ouni, Sophie Saussenthaler, Julian Roos, Laura Stirm, Markus Jähnert, Anne Kamitz, Nicole Hallahan, Wenke Jonas, Andreas Fritsche, Hans-Ulrich Häring, Harald Staiger, Matthias Blüher, Pamela Fischer-Posovszky, Heike Vogel, Annette Schürmann

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Original Research Article
Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivityHao Shi, Alexander Munk, Thomas S. Nielsen, Morgan R. Daughtry, Louise Larsson, Shize Li, Kasper F. Høyer, Hannah W. Geisler, Karolina Sulek, Rasmus Kjøbsted, Taylor Fisher, Marianne M. Andersen, Zhengxing Shen, Ulrik K. Hansen, Eric M. England, Zhiyong Cheng, Kurt Højlund, Jørgen F.P. Wojtaszewski, Xiaoyong Yang, Matthew W. Hulver, Richard F. Helm, Jonas T. Treebak, David E. Gerrard

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Brief Communication
NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesityKaren Nørgaard Nielsen, Julia Peics, Tao Ma, Iuliia Karavaeva, Morten Dall, Sabina Chubanava, Astrid L. Basse, Oksana Dmytriyeva, Jonas T. Treebak, Zachary Gerhart-Hines

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Brief Communication
Vertical sleeve gastrectomy corrects metabolic perturbations in a low-exercise capacity rat modelLandon Wood, Karen Roelofs, Lauren G. Koch, Steven L. Britton, Darleen A. Sandoval

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Brief Communication
Phosphate-dependent FGF23 secretion is modulated by PiT2/Slc20a2Nina Bon, Giulia Frangi, Sophie Sourice, Jérôme Guicheux, Sarah Beck-Cormier, Laurent Beck

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Brief Communication
GPR142 prompts glucagon-like Peptide-1 release from islets to improve β cell functionHua V. Lin, Jingru Wang, Jie Wang, Weiji Li, Xuesong Wang, James T. Alston, Melissa K. Thomas, Daniel A. Briere, Samreen K. Syed, Alexander M. Efanov

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Brief Communication
Overexpression of ST5, an activator of Ras, has no effect on β-cell proliferation in adult miceKristy Ou, Jia Zhang, Yang Jiao, Zhao V. Wang, Phillipp Scherer, Klaus H. Kaestner

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Susan Burke
Pennington Biomedical Research Center, Baton Rouge, LA, USA
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