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Past Issue

Volume 13 | July 2018


Original Research Article
CoDE-seq, an augmented whole-exome sequencing, enables the accurate detection of CNVs and mutations in Mendelian obesity and intellectual disabilityLouise Montagne, Mehdi Derhourhi, Amélie Piton, Bénédicte Toussaint, Emmanuelle Durand, Emmanuel Vaillant, Dorothée Thuillier, Stefan Gaget, Franck De Graeve, Iandry Rabearivelo, Amélie Lansiaux, Bruno Lenne, Sylvie Sukno, Rachel Desailloud, Miriam Cnop, Ramona Nicolescu, Lior Cohen, Jean-François Zagury, Mélanie Amouyal, Jacques Weill, Jean Muller, Olivier Sand, Bruno Delobel, Philippe Froguel, Amélie Bonnefond

Abstract | PDF



Original Research Article
A disease-associated Aifm1 variant induces severe myopathy in knockin mice Lena Wischhof, Anna Gioran, Dagmar Sonntag-Bensch, Antonia Piazzesi, Miriam Stork, Pierluigi Nicotera, Daniele Bano

Abstract | Graphical abstract | PDF



Original Research Article
Surplus fat rapidly increases fat oxidation and insulin resistance in lipodystrophic miceAmandine Girousse, Samuel Virtue, Dan Hart, Antonio Vidal-Puig, Peter R. Murgatroyd, Etienne Mouisel, Coralie Sengenès, David B. Savage

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Original Research Article
Osteoglycin, a novel coordinator of bone and glucose homeostasisN.J. Lee, N. Ali, L. Zhang, Y. Qi, I. Clarke, R.F. Enriquez, M. Brzozowska, I.C. Lee, M.J. Rogers, D.R. Laybutt, J.R. Center, P.A. Baldock, H. Herzog

Abstract | Graphical abstract | PDF



Original Research Article
Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificityArchita Agrawal, Sebastian Parlee, Diego Perez-Tilve, Pengyun Li, Jia Pan, Piotr A. Mroz, Ann Maria Kruse Hansen, Birgitte Andersen, Brian Finan, Alexei Kharitonenkov, Richard D. DiMarchi

Abstract | Graphical abstract | PDF



Original Research Article
Deficiency of fibroblast growth factor 21 (FGF21) promotes hepatocellular carcinoma (HCC) in mice on a long term obesogenic dietGarima Singhal, Gaurav Kumar, Suzanne Chan, ffolliott M. Fisher, Yong Ma, Hilde G. Vardeh, Imad A. Nasser, Jeffrey S. Flier, Eleftheria Maratos-Flier

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Brief Communication
Altered pancreatic islet morphology and function in SGLT1 knockout mice on a glucose-deficient, fat-enriched dietMarkus Mühlemann, Daniela Zdzieblo, Alexandra Friedrich, Constantin Berger, Christoph Otto, Heike Walles, Hermann Koepsell, Marco Metzger

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Brief Communication
Time-resolved hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood–brain barrier in leptin resistant miceMaximilian Kleinert, Petra Kotzbeck, Thomas Altendorfer-Kroath, Thomas Birngruber, Matthias H. Tschöp, Christoffer Clemmensen

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Brief Communication
Functional analysis reveals differential effects of glutamate and MCH neuropeptide in MCH neuronsMarc Schneeberger, Keith Tan, Alexander R. Nectow, Luca Parolari, Caner Caglar, Estefania Azevedo, Zhiying Li, Ana Domingos, Jeffrey M. Friedman

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Editorial Board and Credits


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    Pennington Biomedical Research Center, Baton Rouge, LA, USA
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