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Past Issue

Volume 24 | June 2019


Original Research Article
Identification of functional lipid metabolism biomarkers of brown adipose tissue agingSabrina Gohlke, Vyacheslav Zagoriy, Alvaro Cuadros Inostroza, Michaël Méret, Carola Mancini, Lukasz Japtok, Fabian Schumacher, Doreen Kuhlow, Antonia Graja, Heike Stephanowitz, Markus Jähnert, Eberhard Krause, Andreas Wernitz, Klaus-Jürgen Petzke, Annette Schürmann, Burkhard Kleuser, Tim J. Schulz

Abstract | PDF



Original Research Article
Adipose Lipocalin 2 overexpression protects against age-related decline in thermogenic function of adipose tissue and metabolic deteriorationJessica A. Deis, Hong Guo, Yingjie Wu, Chengyu Liu, David A. Bernlohr, Xiaoli Chen

Abstract | PDF



Original Research Article
Heterogeneity in the perirenal region of humans suggests presence of dormant brown adipose tissue that contains brown fat precursor cellsNaja Z. Jespersen, Amir Feizi, Eline S. Andersen, Sarah Heywood, Helle B. Hattel, Søren Daugaard, Lone Peijs, Per Bagi, Bo Feldt-Rasmussen, Heidi S. Schultz, Ninna S. Hansen, Rikke Krogh-Madsen, Bente K. Pedersen, Natasa Petrovic, Søren Nielsen, Camilla Scheele

Abstract | Graphical abstract | PDF



Original Research Article
Targeted deletion of Tcf7l2 in adipocytes promotes adipocyte hypertrophy and impaired glucose metabolismGisela Geoghegan, Judith Simcox, Marcus M. Seldin, Timothy J. Parnell, Chris Stubben, Steven Just, Lori Begaye, Aldons J. Lusis, Claudio J. Villanueva

Abstract | PDF



Original Research Article
Ferritin regulates organismal energy balance and thermogenesisBirte Blankenhaus, Faouzi Braza, Rui Martins, Patricia Bastos-Amador, Ismael González-García, Ana Rita Carlos, Inês Mahu, Pedro Faisca, Jose Moura Nunes, Pedro Ventura, Verena Hoerr, Sebastian Weis, Joel Guerra, Silvia Cardoso, Ana Domingos, Miguel López, Miguel P. Soares

Abstract | PDF



Original Research Article
Point mutations in the PDX1 transactivation domain impair human β-cell development and functionXianming Wang, Michael Sterr, Ansarullah, Ingo Burtscher, Anika Böttcher, Julia Beckenbauer, Johanna Siehler, Thomas Meitinger, Hans-Ulrich Häring, Harald Staiger, Filippo M. Cernilogar, Gunnar Schotta, Martin Irmler, Johannes Beckers, Christopher V.E. Wright, Mostafa Bakhti, Heiko Lickert

Abstract | PDF



Original Research Article
Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetesAmna Khamis, Mickaël Canouil, Afshan Siddiq, Hutokshi Crouch, Mario Falchi, Manon von Bulow, Florian Ehehalt, Lorella Marselli, Marius Distler, Daniela Richter, Jürgen Weitz, Krister Bokvist, Ioannis Xenarios, Bernard Thorens, Anke M. Schulte, Mark Ibberson, Amelie Bonnefond, Piero Marchetti, Michele Solimena, Philippe Froguel

Abstract | PDF



Original Research Article
Discovering metabolic disease gene interactions by correlated effects on cellular morphologyYang Jiao, Umer Ahmed, M.F. Michelle Sim, Andrea Bejar, Xiaolan Zhang, M. Mesbah Uddin Talukder, Robert Rice, Jason Flannick, Anna I. Podgornaia, Dermot F. Reilly, Jesse M. Engreitz, Maria Kost-Alimova, Kate Hartland, Josep-Maria Mercader, Sara Georges, Vilas Wagh, Marija Tadin-Strapps, John G. Doench, J. Michael Edwardson, Justin J. Rochford, Evan D. Rosen, Amit R. Majithia

Abstract | PDF



Original Research Article
Dopamine neuronal protection in the mouse Substantia nigra by GHSR is independent of electric activityBernardo Stutz, Carole Nasrallah, Mariana Nigro, Daniel Curry, Zhong-Wu Liu, Xiao-Bing Gao, John D. Elsworth, Liat Mintz, Tamas L. Horvath

Abstract | PDF



Brief Communication
Dietary calories and lipids synergistically shape adipose tissue cellularity during postnatal growthIrina Meln, Gretchen Wolff, Thomas Gajek, Johanna Koddebusch, Sarah Lerch, Liza Harbrecht, Wujun Hong, Irem Bayindir-Buchhalter, Damir Krunic, Hellmut G. Augustin, Alexandros Vegiopoulos

Abstract | PDF



Brief Communication
Profound weight loss induces reactive astrogliosis in the arcuate nucleus of obese miceLuke Harrison, Katrin Pfuhlmann, Sonja C. Schriever, Paul T. Pfluger

Abstract | PDF



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Astrid Johannesson Hjelholt
Aarhus University Hospital, Denmark
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