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Past Issue

Volume 6 | No. 11 | November 2017


Original Research Article
The autonomic nervous system and cardiac GLP-1 receptors control heart rate in miceLaurie L. Baggio, John R. Ussher, Brent A. McLean, Xiemin Cao, M. Golam Kabir, Erin E. Mulvihill, Alexandra S. Mighiu, Hangjun Zhang, Andreas Ludwig, Randy J. Seeley, Scott P. Heximer, Daniel J. Drucker

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Original Research Article
Acute activation of GLP-1-expressing neurons promotes glucose homeostasis and insulin sensitivityXuemei Shi, Shaji Chacko, Feng Li, Depei Li, Douglas Burrin, Lawrence Chan, Xinfu Guan

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Original Research Article
Superior reductions in hepatic steatosis and fibrosis with co-administration of a glucagon-like peptide-1 receptor agonist and obeticholic acid in miceHani Jouihan, Sarah Will, Silvia Guionaud, Michelle L. Boland, Stephanie Oldham, Peter Ravn, Anthony Celeste, James L. Trevaskis

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Original Research Article
Host–microbiota interaction induces bi-phasic inflammation and glucose intolerance in miceAntonio Molinaro, Robert Caesar, Louise Mannerås Holm, Valentina Tremaroli, Patrice D. Cani, Fredrik Bäckhed

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Original Research Article
Deletion of hepatic carbohydrate response element binding protein (ChREBP) impairs glucose homeostasis and hepatic insulin sensitivity in miceTara Jois, Weiyi Chen, Victor Howard, Rebecca Harvey, Kristina Youngs, Claudia Thalmann, Pradip Saha, Lawrence Chan, Michael A. Cowley, Mark W. Sleeman

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Original Research Article
Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injuryBhavna N. Desai, Garima Singhal, Mikiko Watanabe, Darko Stevanovic, Thomas Lundasen, ffolliott M. Fisher, Marie L. Mather, Hilde G. Vardeh, Nicholas Douris, Andrew C. Adams, Imad A. Nasser, Garret A. FitzGerald, Jeffrey S. Flier, Carsten Skarke, Eleftheria Maratos-Flier

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Original Research Article
Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetesAnna Motterle, Sonia Gattesco, Marie-Line Peyot, Jonathan Lou S. Esguerra, Ana Gomez-Ruiz, D. Ross Laybutt, Patrick Gilon, Frédéric Burdet, Mark Ibberson, Lena Eliasson, Marc Prentki, Romano Regazzi

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Original Research Article
Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxietyLee Moir, Elena G. Bochukova, Rebecca Dumbell, Gareth Banks, Rasneer S. Bains, Patrick M. Nolan, Cheryl Scudamore, Michelle Simon, Kimberly A. Watson, Julia Keogh, Elana Henning, Audrey Hendricks, Stephen O'Rahilly, Inês Barroso, UK10K consortium, Adrienne E. Sullivan, David C. Bersten, Murray L. Whitelaw, Susan Kirsch, Elizabeth Bentley, I. Sadaf Farooqi, Roger D. Cox

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Original Research Article
An unbiased silencing screen in muscle cells identifies miR-320a, miR-150, miR-196b, and miR-34c as regulators of skeletal muscle mitochondrial metabolismDennis Dahlmans, Alexandre Houzelle, Pénélope Andreux, Johanna A. Jörgensen, Xu Wang, Leon J. de Windt, Patrick Schrauwen, Johan Auwerx, Joris Hoeks

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Original Research Article
Absence of the kinase S6k1 mimics the effect of chronic endurance exercise on glucose tolerance and muscle oxidative stressC. Binsch, T. Jelenik, A. Pfitzer, M. Dille, S. Müller-Lühlhoff, S. Hartwig, S. Karpinski, S. Lehr, D.G. Kabra, A. Chadt, M. Roden, H. Al-Hasani, T.R. Castañeda

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Original Research Article
FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytesMark Z. Chen, Joshua C. Chang, Jose Zavala-Solorio, Lance Kates, Minh Thai, Annie Ogasawara, Xiaobo Bai, Sean Flanagan, Victor Nunez, Khanhky Phamluong, James Ziai, Robert Newman, Søren Warming, Ganesh Kolumam, Junichiro Sonoda

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Original Research Article
The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacityAdam J. Rauckhorst, Lawrence R. Gray, Ryan D. Sheldon, Xiaorong Fu, Alvin D. Pewa, Charlotte R. Feddersen, Adam J. Dupuy, Katherine N. Gibson-Corley, James E. Cox, Shawn C. Burgess, Eric B. Taylor

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Original Research Article
Amino acid sensing in hypothalamic tanycytes via umami taste receptorsGreta Lazutkaite, Alice Soldà, Kristina Lossow, Wolfgang Meyerhof, Nicholas Dale

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Original Research Article
The FGF21 response to fructose predicts metabolic health and persists after bariatric surgery in obese humansKasper W. ter Horst, Pim W. Gilijamse, Ahmet Demirkiran, Bart A. van Wagensveld, Mariette T. Ackermans, Joanne Verheij, Johannes A. Romijn, Max Nieuwdorp, Eleftheria Maratos-Flier, Mark A. Herman, Mireille J. Serlie

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Original Research Article
Maternal obesity alters fatty acid oxidation, AMPK activity, and associated DNA methylation in mesenchymal stem cells from human infantsKristen E. Boyle, Zachary W. Patinkin, Allison L.B. Shapiro, Carly Bader, Lauren Vanderlinden, Katerina Kechris, Rachel C. Janssen, Rebecca J. Ford, Brennan K. Smith, Gregory R. Steinberg, Elizabeth J. Davidson, Ivana V. Yang, Dana Dabelea, Jacob E. Friedman

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Original Research Article
Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese miceTony Jourdan, Sarah M. Nicoloro, Zhou Zhou, Yuefei Shen, Jie Liu, Nathan J. Coffey, Resat Cinar, Grzegorz Godlewski, Bin Gao, Myriam Aouadi, Michael P. Czech, George Kunos

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Original Research Article
KLK5 induces shedding of DPP4 from circulatory Th17 cells in type 2 diabetesTitli Nargis, Krishna Kumar, Amrit Raj Ghosh, Amit Sharma, Dipayan Rudra, Debrup Sen, Saikat Chakrabarti, Satinath Mukhopadhyay, Dipyaman Ganguly, Partha Chakrabarti

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Original Research Article
Bombesin-like receptor 3 (Brs3) expression in glutamatergic, but not GABAergic, neurons is required for regulation of energy metabolismCuiying Xiao, Ramón A. Piñol, Jesse Lea Carlin, Cuiling Li, Chuxia Deng, Oksana Gavrilova, Marc L. Reitman

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Original Research Article
Adult neural stem cell fate is determined by thyroid hormone activation of mitochondrial metabolismJ.D. Gothié, A. Sébillot, C. Luongo, M. Legendre, C. Nguyen Van, K. Le Blay, M. Perret-Jeanneret, S. Remaud, B.A. Demeneix

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Corrigendum
Corrigendum to “Insulin controls food intake and energy balance via NPY neurons” [Mol Metabol 6 (2017) 574–584]Kim Loh, Lei Zhang, Amanda Brandon, Qiaoping Wang, Denovan Begg, Yue Qi, Melissa Fu, Rishikesh Kulkarni, Jonathan Teo, Paul Baldock, Jens C. Bruning, Gregory Cooney, Greg G. Neely, Herbert Herzog

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