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Past Issue

Volume 8 | February 2018


Original Research Article
Differential contribution of POMC and AgRP neurons to the regulation of regional autonomic nerve activity by leptinBalyssa B. Bell, Shannon M. Harlan, Donald A. Morgan, Deng-Fu Guo, Kamal Rahmouni

Abstract | Graphical abstract | PDF



Original Research Article
The LepR-mediated leptin transport across brain barriers controls food rewardAlessandro Di Spiezio, Elvira Sonia Sandin, Riccardo Dore, Helge Müller-Fielitz, Steffen E. Storck, Mareike Bernau, Walter Mier, Henrik Oster, Olaf Jöhren, Claus U. Pietrzik, Hendrik Lehnert, Markus Schwaninger

Abstract | Graphical abstract | PDF



Original Research Article
Inhibition of central de novo ceramide synthesis restores insulin signaling in hypothalamus and enhances β-cell function of obese Zucker ratsMélanie Campana, Lara Bellini, Claude Rouch, Latif Rachdi, Nicolas Coant, Noémie Butin, Cécile L. Bandet, Erwann Philippe, Kelly Meneyrol, Nadim Kassis, Julien Dairou, Eric Hajduch, Benoit Colsch, Christophe Magnan, Hervé Le Stunff

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Original Research Article
A gut–brain axis regulating glucose metabolism mediated by bile acids and competitive fibroblast growth factor actions at the hypothalamusShunmei Liu, Genevieve Marcelin, Clemence Blouet, Jae Hoon Jeong, Young-Hwan Jo, Gary J. Schwartz, Streamson Chua Jr.

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Original Research Article
Adropin: An endocrine link between the biological clock and cholesterol homeostasisSarbani Ghoshal, Joseph R. Stevens, Cyrielle Billon, Clemence Girardet, Sadichha Sitaula, Arthur S. Leon, D.C. Rao, James S. Skinner, Tuomo Rankinen, Claude Bouchard, Marinelle V. Nuñez, Kimber L. Stanhope, Deborah A. Howatt, Alan Daugherty, Jinsong Zhang, Matthew Schuelke, Edward P. Weiss, Alisha R. Coffey, Brian J. Bennett, Praveen Sethupathy, Thomas P. Burris, Peter J. Havel, Andrew A. Butler

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Original Research Article
Cdkn2a deficiency promotes adipose tissue browningNabil Rabhi, Sarah Anissa Hannou, Xavier Gromada, Elisabet Salas, Xi Yao, Frédérik Oger, Charlène Carney, Isabel C. Lopez-Mejia, Emmanuelle Durand, Iandry Rabearivelo, Amélie Bonnefond, Emilie Caron, Lluis Fajas, Christian Dani, Philippe Froguel, Jean-Sébastien Annicotte

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Original Research Article
Degradation of brown adipocyte purine nucleotides regulates uncoupling protein 1 activityTobias Fromme, Karin Kleigrewe, Andreas Dunkel, Angelika Retzler, Yongguo Li, Stefanie Maurer, Natascha Fischer, Rolf Diezko, Timo Kanzleiter, Verena Hirschberg, Thomas Hofmann, Martin Klingenspor

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Original Research Article
Elevating adipose eosinophils in obese mice to physiologically normal levels does not rescue metabolic impairmentsW. Reid Bolus, Kristin R. Peterson, Merla J. Hubler, Arion J. Kennedy, Marnie L. Gruen, Alyssa H. Hasty

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Original Research Article
The RhoGAP Stard13 controls insulin secretion through F-actin remodelingHeike Naumann, Thomas Rathjen, Matthew N. Poy, Francesca M. Spagnoli

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Original Research Article
Hepatocyte estrogen receptor alpha mediates estrogen action to promote reverse cholesterol transport during Western-type diet feedingLin Zhu, Jeanne Shi, Thao N. Luu, Joshua C. Neuman, Elijah Trefts, Sophia Yu, Brian T. Palmisano, David H. Wasserman, MacRae F. Linton, John M. Stafford

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Original Research Article
Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver diseaseMohammad Zarei, Emma Barroso, Xavier Palomer, Jianli Dai, Patricia Rada, Tania Quesada-López, Joan Carles Escolà-Gil, Lidia Cedó, Mohammad Reza Zali, Mahsa Molaei, Reza Dabiri, Santiago Vázquez, Eugènia Pujol, Ángela M. Valverde, Francesc Villarroya, Yong Liu, Walter Wahli, Manuel Vázquez-Carrera

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Original Research Article
Pharmacological stimulation of p53 with low-dose doxorubicin ameliorates diet-induced nonalcoholic steatosis and steatohepatitisBegoña Porteiro, Marcos F. Fondevila, Xabier Buque, Maria J. Gonzalez-Rellan, Uxia Fernandez, Alfonso Mora, Daniel Beiroa, Ana Senra, Rosalia Gallego, Johan Fernø, Miguel López, Guadalupe Sabio, Carlos Dieguez, Patricia Aspichueta, Rubén Nogueiras

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Original Research Article
The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidatesVioleta Georgieva Tsonkova, Fredrik Wolfhagen Sand, Xenia Asbæk Wolf, Lars Groth Grunnet, Anna Kirstine Ringgaard, Camilla Ingvorsen, Louise Winkel, Mark Kalisz, Kevin Dalgaard, Christine Bruun, Johannes Josef Fels, Charlotte Helgstrand, Sven Hastrup, Fredrik Kryh Öberg, Erik Vernet, Michael Paolo Bastner Sandrini, Allan Christian Shaw, Carsten Jessen, Mads Grønborg, Jacob Hald, Hanni Willenbrock, Dennis Madsen, Rasmus Wernersson, Lena Hansson, Jan Nygaard Jensen, Annette Plesner, Tomas Alanentalo, Maja Borup Kjær Petersen, Anne Grapin-Botton, Christian Honoré, Jonas Ahnfelt-Rønne, Jacob Hecksher-Sørensen, Philippe Ravassard, Ole D. Madsen, Claude Rescan, Thomas Frogne

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Original Research Article
Androgen receptor overexpression in prostate cancer in type 2 diabetesStefan Zoltán Lutz, Jörg Hennenlotter, Marcus Oliver Scharpf, Corinna Sailer, Louise Fritsche, Vera Schmid, Konstantinos Kantartzis, Robert Wagner, Rainer Lehmann, Lucia Berti, Andreas Peter, Harald Staiger, Andreas Fritsche, Falko Fend, Tilman Todenhöfer, Arnulf Stenzl, Hans-Ulrich Häring, Martin Heni

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Original Research Article
Adiponectin release and insulin receptor targeting share trans-Golgi-dependent endosomal trafficking routesMaria Rödiger, Martin W. Werno, Ilka Wilhelmi, Christian Baumeier, Deike Hesse, Nina Wettschureck, Stefan Offermanns, Kyungyeun Song, Michael Krauß, Annette Schürmann

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Original Research Article
Cadm2 regulates body weight and energy homeostasis in miceXin Yan, Zhen Wang, Vanessa Schmidt, Anton Gauert, Thomas E. Willnow, Matthias Heinig, Matthew N. Poy

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Original Research Article
Targeting erythropoietin protects against proteinuria in type 2 diabetic patients and in zebrafishJianqing She, Zuyi Yuan, Yue Wu, Junfang Chen, Jens Kroll

Abstract | Graphical abstract | PDF



Review
Amylin – Its role in the homeostatic and hedonic control of eating and recent developments of amylin analogs to treat obesityChristina Neuner Boyle, Thomas Alexander Lutz, Christelle Le Foll

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Commentary
Central leptin and autonomic regulation: A melanocortin businessMiguel López

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Editorial Board and Credits


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