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Volume 7 | No. 1 | January 2018


Original Research Article
Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise enduranceSheila R. Costford, Bram Brouwers, Meghan E. Hopf, Lauren M. Sparks, Mauro Dispagna, Ana P. Gomes, Heather H. Cornnell, Chris Petucci, Peter Phelan, Hui Xie, Fanchao Yi, Glenn A. Walter, Timothy F. Osborne, David A. Sinclair, Randall L. Mynatt, Julio E. Ayala, Stephen J. Gardell, Steven R. Smith

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Original Research Article
Neurturin is a PGC-1α1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formationRichard Mills, Hermes Taylor-Weiner, Jorge C. Correia, Leandro Z. Agudelo, Ilary Allodi, Christina Kolonelou, Vicente Martinez-Redondo, Duarte M.S. Ferreira, Susanne Nichterwitz, Laura H. Comley, Vanessa Lundin, Eva Hedlund, Jorge L. Ruas, Ana I. Teixeira

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Original Research Article
Macrophages sensing oxidized DAMPs reprogram their metabolism to support redox homeostasis and inflammation through a TLR2-Syk-ceramide dependent mechanismVlad Serbulea, Clint M. Upchurch, Katelyn W. Ahern, Gael Bories, Paxton Voigt, Dory E. DeWeese, Akshaya K. Meher, Thurl E. Harris, Norbert Leitinger

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Original Research Article
Mitochondrial fission is associated with UCP1 activity in human brite/beige adipocytesDidier F. Pisani, Valentin Barquissau, Jean-Claude Chambard, Diane Beuzelin, Rayane A. Ghandour, Maude Giroud, Aline Mairal, Sophie Pagnotta, Saverio Cinti, Dominique Langin, Ez-Zoubir Amri

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Original Research Article
Fatty acid oxidation is required for active and quiescent brown adipose tissue maintenance and thermogenic programingElsie Gonzalez-Hurtado, Jieun Lee, Joseph Choi, Michael J. Wolfgang

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Original Research Article
Vacuolar protein sorting 13C is a novel lipid droplet protein that inhibits lipolysis in brown adipocytesVanesa D. Ramseyer, Victoria A. Kimler, James G. Granneman

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Original Research Article
Constant hepatic ATP concentrations during prolonged fasting and absence of effects of Cerbomed Nemos® on parasympathetic tone and hepatic energy metabolismSofiya Gancheva, Alessandra Bierwagen, Daniel F. Markgraf, Gidon J. Bönhof, Kevin G. Murphy, Erifili Hatziagelaki, Jesper Lundbom, Dan Ziegler, Michael Roden

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Original Research Article
Metabolic adaptation to intermittent fasting is independent of peroxisome proliferator-activated receptor alphaGuolin Li, Chad N. Brocker, Tingting Yan, Cen Xie, Kristopher W. Krausz, Rong Xiang, Frank J. Gonzalez

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Original Research Article
Mechanistic insights into the detection of free fatty and bile acids by ileal glucagon-like peptide-1 secreting cellsDeborah A. Goldspink, Van B. Lu, Lawrence J. Billing, Pierre Larraufie, Gwen Tolhurst, Fiona M. Gribble, Frank Reimann

Abstract | Graphical abstract | PDF



Original Research Article
CART neurons in the arcuate nucleus and lateral hypothalamic area exert differential controls on energy homeostasisJackie Lau, Aitak Farzi, Yue Qi, Regine Heilbronn, Mario Mietzsch, Yan-Chuan Shi, Herbert Herzog

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Original Research Article
PGC-1α functions as a co-suppressor of XBP1s to regulate glucose metabolismJaemin Lee, Mario Andrés Salazar Hernández, Thomas Auen, Patrick Mucka, Justin Lee, Umut Ozcan

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Original Research Article
Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitisÁgueda González-Rodríguez, M. Pilar Valdecantos, Patricia Rada, Annalisa Addante, Inés Barahona, Esther Rey, Virginia Pardo, Laura Ruiz, Laura M. Laiglesia, María J. Moreno-Aliaga, Carmelo García-Monzón, Aránzazu Sánchez, Ángela M. Valverde

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Original Research Article
Why lipostatic set point systems are unlikely to evolveJohn R. Speakman

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Brief Communication
Deficiency of leptin receptor in myeloid cells disrupts hypothalamic metabolic circuits and causes body weight increaseYuanqing Gao, Andrés Vidal-Itriago, Irina Milanova, Nikita L. Korpel, Martin J. Kalsbeek, Robby Zachariah Tom, Andries Kalsbeek, Susanna M. Hofmann, Chun-Xia Yi

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Brief Communication
Optimal housing temperatures for mice to mimic the thermal environment of humans: An experimental studyAlexander W. Fischer, Barbara Cannon, Jan Nedergaard

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Michael Tarpey
Virginia Tech, Blacksburg, VA, USA
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Organ Crosstalk in Obesity and NAFLD
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