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Volume 32 | February 2020


Review
Physical exercise and liver “fitness”: Role of mitochondrial function and epigenetics-related mechanisms in non-alcoholic fatty liver diseaseJelena Stevanović, Jorge Beleza, Pedro Coxito, António Ascensão, José Magalhães

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Original Research Article
BMP4 gene therapy enhances insulin sensitivity but not adipose tissue browning in obese miceJenny M. Hoffmann, John R. Grünberg, Ann Hammarstedt, Tobias Kroon, Thomas U. Greiner, Stefanie Maurer, Ivet Elias, Vilborg Palsdottir, Fatima Bosch, Jeremie Boucher, Shahram Hedjazifar, Ulf Smith

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Original Research Article
The carbohydrate-insulin model does not explain the impact of varying dietary macronutrients on the body weight and adiposity of miceSumei Hu, Lu Wang, Jacques Togo, Dengbao Yang, Yanchao Xu, Yingga Wu, Alex Douglas, John R. Speakman

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Original Research Article
Pharmacological antagonism of the incretin system protects against diet-induced obesityBerit Svendsen, Megan E. Capozzi, Jingjing Nui, Sarah A. Hannou, Brian Finan, Jacqueline Naylor, Peter Ravn, David A. D'Alessio, Jonathan E. Campbell

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Original Research Article
Regulation of muscle and metabolic physiology by hypothalamic erythropoietin independently of its peripheral actionZhouguang Wang, Sinan Khor, Dongsheng Cai

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Original Research Article
Fasting induces remodeling of the orexigenic projections from the arcuate nucleus to the hypothalamic paraventricular nucleus, in a growth hormone secretagogue receptor–dependent mannerAgustina Cabral, Gimena Fernandez, María J. Tolosa, Ángeles Rey Moggia, Gastón Calfa, Pablo N. De Francesco, Mario Perello

Abstract | Graphical abstract | PDF



Original Research Article
SWI/SNF complex subunit BAF60a represses hepatic ureagenesis through a crosstalk between YB-1 and PGC-1αWenxiang Zhang, Zhewen Dong, Mengyi Xu, Shiyao Zhang, Chang Liu, Siyu Chen

Abstract | Graphical abstract | PDF



Original Research Article
Hepatic ERα accounts for sex differences in the ability to cope with an excess of dietary lipidsClara Meda, Mara Barone, Nico Mitro, Federica Lolli, Silvia Pedretti, Donatella Caruso, Adriana Maggi, Sara Della Torre

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Original Research Article
Single-cell ATAC-Seq in human pancreatic islets and deep learning upscaling of rare cells reveals cell-specific type 2 diabetes regulatory signaturesVivek Rai, Daniel X. Quang, Michael R. Erdos, Darren A. Cusanovich, Riza M. Daza, Narisu Narisu, Luli S. Zou, John P. Didion, Yuanfang Guan, Jay Shendure, Stephen C.J. Parker, Francis S. Collins

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Original Research Article
Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injuryThekla Cordes, Alfredo Lucas, Ajit S. Divakaruni, Anne N. Murphy, Pedro Cabrales, Christian M. Metallo

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Original Research Article
mTORC1 restrains adipocyte lipolysis to prevent systemic hyperlipidemiaLauren M. Paolella, Sarmistha Mukherjee, Cassie M. Tran, Bruna Bellaver, Mindy Hugo, Timothy S. Luongo, Swapnil V. Shewale, Wenyun Lu, Karthikeyani Chellappa, Joseph A. Baur

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Original Research Article
Continuous glucose monitoring reveals glycemic variability and hypoglycemia after vertical sleeve gastrectomy in ratsSimon S. Evers, Ki-Suk Kim, Nadejda Bozadjieva, Alfor G. Lewis, Diana Farris, Matthew J. Sorensen, Youngsoo Kim, Steven E. Whitesall, Robert T. Kennedy, Daniel E. Michele, Randy J. Seeley, Darleen A. Sandoval

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Original Research Article
Identification of the leptin receptor sequences crucial for the STAT3-Independent control of metabolismTammy M. Barnes, Kimi Shah, Margaret B. Allison, Gabrielle K. Steinl, Desiree Gordian, Paul V. Sabatini, Abigail J. Tomlinson, Wenwen Cheng, Justin C. Jones, Qing Zhu, Chelsea Faber, Martin G. Myers Jr.

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Brief Communication
Glucocorticoid induces human beta cell dysfunction by involving riborepressor GAS5 LincRNAJonathan L.S. Esguerra, Jones K. Ofori, Mototsugu Nagao, Yuki Shuto, Alexandros Karagiannopoulos, Joao Fadista, Hitoshi Sugihara, Leif Groop, Lena Eliasson

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Editorial Board and Credits


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Articles in Press

The 60 Second Metabolist
In this section authors briefly report on their work recently published in Molecular Metabolism.

Watch the most recent interview by clicking the video still. The link "referring article" directs you to this author's publication.



Ulf Smith, John Grünberg, Tobias Kroon
Sahlgrenska Academy, University of Gothenburg, Sweden
Referring article

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Conferences & Events
February
23 − 27
2020
Keystone Sym­posium:
Obesity and NAFLD

Banff, Canada
February
24 − 27
2020
2nd Nuclear Receptors Conference
Nassau, Bahamas
March
1 − 5
2020
Keystone Sym­posium:
Biology of Exercise

Keystone, USA
March
10 − 11
2020
Dutch Translational Metabolism Conference
Lunteren, Netherlands
March
8 − 12
2020
Keystone Sym­posium:
Tumor Metabolism

Banff, Canada
March
22 − 26
2020
Keystone Sym­posium:
Gut-Systemic Perspective of Metabolic Disease

Santa Fe, USA
April
3 − 7
2020
Keystone Sym­posium:
Metabolism and Immunity

Keystone, USA
April
22 − 24
2020
Helmholtz:
Pseudokinases and Tribbles

Munich, Germany
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